OA KNEE - Dissertations.se

Knee cartilage quality assessed with dGEMRIC in rheumatoid

436-442 “Out-of-Pocket X-Ray, CT Scan Costs Vary Widely”, He-. althDay, 2016. Förutom tryckning hjälper vi dig med sättning, omslagslayout och scanning dGEMrIC analysis and contrast distribution in clinical studies of Scan- dinavian Journal of Medicine and Science in. Sport, 19,3, 442-452. Söderman, K., Pietila, T., magnetkameraundersökning (3D dGEMRIC). 145 000. Blåsfunktion bedöms med t.ex. bladder scan eller KAD-sättning.

Dgemric scan

dGEMRIC and T2 mapping. Three hips were excluded as a result of incomplete scans owing to a software upgrade for. Fig. 5 Jun 2020 Images were analyzed by two independent raters for dGEMRIC indices, Conclusion: As examined by DCE MRI and dGEMRIC, there is a significant Use precise geolocation data, Actively scan device characteristics for Clinical examination, serum COMP level, and dGEMRIC scans (1.5 T) were performed at baseline and after 7 months. The dGEMRIC index (ms), reflecting av C Siversson — dGEMRIC delayed gadolinium-enhanced MRI of cartilage.

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Materials and Methods Patient Selection P atients who underwent primary hip arthroscopy between August 2008 and August 2012, and whohad a preoperative dGEMRIC scan of the hip However, its highly structured matrix results in a very fast T2 MRI relaxation time, and hence has not been well visualized in dGEMRIC scans. The recent development of fast Spoiled Gradient Echo (fSPGR) 3D T1 mapping pulse sequences for dGEMRIC (3,4) has resulted in echo times under 3.0 millisecond, allowing for calculation of T1(Gd) of the meniscus. 2015-08-25 dGEMRIC scan with an additional T2 mapping sequence at our institution between December 2013 and February 2015 (inclusive) yielded 269 patients.

OA KNEE - Dissertations.se

Since the time Regarding presurgical MRI, patients underwent a dGEMRIC scan an average of 2.3 ± 1.5 months before surgery and ranging from 1 day to 6 months. From our surgical hip registry, we identified 68 hips that underwent surgery between January 2009 and December 2013 (inclusive) and also had a 3-D 1.5-T dGEMRIC scan within 6 months preoperatively.

The primary aim of this study was to show that the dGEMRIC technique is able to monitor cartilage repair following regenerative cartilage treatment. We hypothesized that higher dGEMRIC values, indicating a lower severity of chondromalacia, would be asso-ciated with greater improvements in patient-reported outcome measures.
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The femoral head cartilage is intact (color code: white —T1 1,200 ms, black —T1 200 ms) Contrast Administration and Timing of Imaging in Clinical Studies Osteoarthritis was defined as a dGEMRIC value of <390 msec (two standard deviations below the dGEMRIC index in normal hips). Results: The mean dGEMRIC index (and standard deviation) for this cohort (473 +/- 104 msec) was significantly lower than that of a morphologically normal hip (570 +/- 90 msec). The anterior center-edge angle, the joint space The biochemical information provided by dGEMRIC scans may augment radiography by improving the differentiation of disease status within a given radiographic grade, especially in early OA. Per MRI scan several regions-of-interest (ROIs) were defined for different locations in the joint. The dGEMRIC index (T1gd) was calculated for each ROI. Repeated-measures analysis of variance (RMANOVA) analysis was used to evaluate improvement in clinical scores and MRI T1gd over time.

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For the odd-numbered subjects, the ACL-injured knee was scanned first. For the even-numbered subjects, the uninjured knee was scanned first.

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After a 30 minute delay dGEMRIC scans(14) were obtained using both inversion recovery and fast T1 mapping sequences. dGEMRIC assessment dGEMRIC images were obtained for the study hip on a 3T scanner (Philips Integra) at a single centre. Subjects received intravenous injection of 0.4 ml/kg of Gd-DTPA2- contrast agent (Bayer AG, Leverkusen, Germany) and then performed 10 minutes of weightbearing exercise. OBJECTIVE: Delayed gadolinium enhanced magnetic resonance imaging (MRI) of cartilage (dGEMRIC) facilitates non-invasive evaluation of the glycosaminoglycan content in articular cartilage. The primary aim of this study was to show that the dGEMRIC technique is able to monitor cartilage repair following regenerative cartilage treatment. We hypothesized that higher dGEMRIC values, indicating a lower severity of chondromalacia, would be asso-ciated with greater improvements in patient-reported outcome measures. Materials and Methods Patient Selection P atients who underwent primary hip arthroscopy between August 2008 and August 2012, and whohad a preoperative dGEMRIC scan of the hip However, its highly structured matrix results in a very fast T2 MRI relaxation time, and hence has not been well visualized in dGEMRIC scans.

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All dGEMRIC scans were performed on a 1.5-T clinical MRI scanner (Achieva, Philips Healthcare, Best, The Netherlands) using a dedicated eight-element sense knee coil as a receiver (Philips Healthcare, Best, The Netherlands). Three-dimensional (3-D) delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) helps quantify biochemical changes in articular cartilage that correlate with early-stage osteoarthritis. However, dGEMRIC analysis is performed slice by slice, limiting the potential of 3-D data to give an overall impression of cartilage biochemistry. In particular, molecular scans such as dGEMRIC have demonstrated “lesions” or generally low values in radiographically normal compartments [51, 62, 64], which has implications for the enrollment of such individuals as “controls” in natural history or intervention trials for cartilage disease. The delayed Gadolinium Enhanced MRI of Cartilage (dGEMERIC) is a functional MRI technique that was designed to detect the loss of the charged extracellular matrix in cartilage in early OA (1, 2). Cartilage fixed‐negative‐charge density is composed of negatively charged glycosaminoglycans. The dGEMRIC scan shows fairly extensive acetabular cartilage damage as indicated by dark red and black regions in the acetabular cartilage.

Index comparisons were made between knee status (ACL-injured vs uninjured), scan order (ACL-injured first vs uninjured first), and cartilage location (tibia vs femur) using a mixed model. Design Thirty-one patients with a focal cartilage lesion underwent a dGEMRIC scan prior to cartilage repair surgery and at 3 and 12 months follow-up.